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In 12 months, only 0.2% of the participants became pregnant.
#Mirena iud hormones trial
In one trial of 1,169 people aged 18–35, the 5-year pregnancy rate was 0.7%.
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The Mirena IUD has several key advantages. This synthetic hormone can also prevent ovulation, though it does not always have this effect. Levonorgestrel works by thickening the cervical mucus and thinning the lining of the uterus, which prevents pregnancy from taking place. The Mirena IUD releases the hormone levonorgestrel, a synthetic form of progesterone. The study’s finding does not necessarily prove that the IUD causes a person to gain weight. However, many factors can influence weight gain, including age. This may indicate that the synthetic hormone in the Mirena IUD leads to a slight gain in weight. After 60 months, this figure rose to 1.52 kg - twice the amount that participants using the copper IUD had gained. In a diverse cohort of women, the researchers investigated the effects of the hormonal IUD, the copper IUD, and the birth control implant on weight gain.Īfter 36 months, hormonal IUD users gained 0.72 kilograms (kg) on average. However, most studies have not found a conclusive link between hormonal IUDs, such as Mirena, and weight gain.Ī 2020 study comparing hormonal IUDs to another form of progesterone-only contraception, the injection, reported that participants using the injection gained weight while those with the IUD did not.Īnother 2020 study found different results. Some people report weight gain while using the Mirena IUD.